ZFIN ID: ZDB-GENE-030131-5391
Gene Name: spastic paraplegia 7
Gene Symbol: spg7
Previous Names: fd15f08, wu:fd15f08
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa10238 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa17610 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21092 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH spg7 HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    hereditary spastic paraplegia Spastic paraplegia 7, autosomal recessive 607259
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process proteolysis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000642 (1)
  • InterPro:IPR003593 (1)
  • InterPro:IPR003959 (1)
  • InterPro:IPR005936 (1)
  • InterPro:IPR011546 (1)
  • InterPro:IPR027417 (1)
  • Pfam:PF00004 (1)
  • Pfam:PF01434 (1)
  • Pfam:PF06480 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA spg7-001 (1) 3109
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM spg7 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    spg7Contained in: [BAC] CH211-89N7 (1) (order this), CH211-245P24 (1) (order this)
    spg7Encodes: [EST] fd15f08
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_001923083 (1) 3152bp
    Genomic GenBank:BX470191 (1) 181294bp
    Select Tool
    Polypeptide UniProtKB:E7F2S4 (1) 788aa
    Sequence Clusters UniGene:105782 (1)
    Sequence Information (all 12)
    OTHER spg7 GENE PAGES 
  • Gene:794740 (1)
  • VEGA:OTTDARG00000035493 (1)
  • Ensembl(GRCz10):ENSDARG00000068187 (1)
  • ORTHOLOGY for spg7 (Chr: 7) 
    Species Symbol Chromosome Accession # Evidence
    Human SPG7 16
  • Gene:6687
  • OMIM:602783
  • HGNC:11237
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Spg7 8
  • MGI:2385906
  • Gene:234847
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (12)