Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-5391
Gene Name: spastic paraplegia 7
Gene Symbol: spg7
Previous Names: fd15f08, wu:fd15f08
Location: Chr: 7   Details
Nomenclature History
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa10238, sa17610, sa21092
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Spastic paraplegia 7, autosomal recessive 607259
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Cellular Component integral component of membrane (more)
Molecular Function ATP binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000642 (1)
  • InterPro:IPR003593 (1)
  • InterPro:IPR003959 (1)
  • InterPro:IPR005936 (1)
  • InterPro:IPR011546 (1)
  • InterPro:IPR027417 (1)
  • Pfam:PF00004 (1)
  • Pfam:PF01434 (1)
  • Pfam:PF06480 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA spg7-001 (1) 3109
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM spg7 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    spg7 Contained in: [BAC] CH211-89N7 (1) (order this), CH211-245P24 (1) (order this)
    spg7 Encodes: [EST] fd15f08
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_001923083 (1) 3181 bp
    Genomic GenBank:BX470191 (1) 181294 bp
    Select Tool
    Polypeptide UniProtKB:E7F2S4 (1) 788 aa
    Sequence Clusters UniGene:105782 (1)
    Sequence Information (all 12)
    OTHER spg7 GENE PAGES
  • Gene:794740 (1)
  • VEGA:OTTDARG00000035493 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish spg7 7  
    Human SPG7 16 (16q24.3)
  • OMIM:602783
  • Gene:6687
  • Mouse Spg7 8 ( 72.04 cM)
  • MGI:2385906
  • Gene:234847
  • Orthology Details
    CITATIONS (9)