ZFIN ID: ZDB-GENE-030131-5366
Gene Name: chromatin assembly factor 1, subunit A (p150)
Gene Symbol: chaf1a    Nomenclature History

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Previous Names: wu:fd14g10, zgc:153930

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to be involved in nucleosome assembly. Predicted to localize to CAF-1 complex and nucleus. Is expressed in several structures, including eye; pectoral fin; pharyngeal arch 3-7 skeleton; somite; and ventricular zone. Human ortholog(s) of this gene implicated in colon cancer; malignant glioma; neuroblastoma; and systemic lupus erythematosus. Orthologous to human CHAF1A (chromatin assembly factor 1 subunit A).
Genome Resources: Alliance (1),  Gene:563212 (1),  Ensembl(GRCz11):ENSDARG00000062152 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (9 images) from Thisse et al., 2004 [IMAGE:7149897]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa3192 Point Mutation Unknown Premature Stop ENU
sa18462 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa29775 Point Mutation Unknown Premature Stop ENU
    sa43835 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43836 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-chaf1a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH chaf1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH chaf1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chromatin assembly (more)
    Cellular Component CAF-1 complex (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA chaf1a-202 (1)    Ensembl 3473
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM chaf1a No data available
    MARKER RELATIONSHIPS
    chaf1a Contained in: [BAC] CH211-129C21 (1)
    chaf1a Encodes: [EST] fd14g10, IMAGE:7149897 (1)
    [cDNA] MGC:153930 (1), MGC:192763 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045013 (1) 3223 nt
    Genomic GenBank:AL935286 (1) 211297 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0JMK9 (1) 863 aa
    Sequence Information (all 26)
    ORTHOLOGY for chaf1a ( Chr: 22 )
    CITATIONS (25)