Gene

ago4

ID
ZDB-GENE-030131-5357
Name
argonaute RISC component 4
Symbol
ago4 Nomenclature History
Previous Names
  • Ago4 (1)
  • eif2c4
  • fd14f04
  • wu:fd14f04
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable miRNA binding activity. Predicted to be involved in miRNA mediated inhibition of translation. Predicted to act upstream of or within gene silencing by RNA and regulation of translation. Predicted to be located in P-body. Predicted to be part of RISC complex. Is expressed in several structures, including eye; fin; integument; pleuroperitoneal region; and somite. Orthologous to human AGO4 (argonaute RISC component 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ago4 Human Ortholog
No data available
Associated With ago4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003100 PAZ domain
Domain IPR003165 Piwi domain
Domain IPR014811 Argonaute, linker 1 domain
Domain IPR032472 Argonaute linker 2 domain
Domain IPR032473 Protein argonaute, Mid domain
Domain IPR032474 Protein argonaute, N-terminal
Family IPR028604 Protein argonaute-4
Homologous_superfamily IPR012337 Ribonuclease H-like superfamily
Homologous_superfamily IPR036085 PAZ domain superfamily
Homologous_superfamily IPR036397 Ribonuclease H superfamily
Domain Details Per Protein
Protein Length Argonaute, linker 1 domain Argonaute linker 2 domain PAZ domain PAZ domain superfamily Piwi domain Protein argonaute-4 Protein argonaute, Mid domain Protein argonaute, N-terminal Ribonuclease H-like superfamily Ribonuclease H superfamily
UniProtKB:K4IAH1 863
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations