ZFIN ID: ZDB-GENE-030131-5345
Gene Name: Tnf receptor-associated factor 2b
Gene Symbol: traf2b    Nomenclature History

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Previous Names: fd14c07, si:dkey-170o10.1 (1), wu:fd14c07

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have tumor necrosis factor receptor binding activity; ubiquitin protein ligase binding activity; and ubiquitin-protein transferase activity. Predicted to be involved in positive regulation of intracellular signal transduction; protein K63-linked ubiquitination; and tumor necrosis factor-mediated signaling pathway. Predicted to localize to cytoplasmic side of plasma membrane and plasma membrane signaling receptor complex. Orthologous to human TRAF2 (TNF receptor associated factor 2).
Genome Resources: Alliance (1),  Gene:557526 (1),  Ensembl(GRCz11):ENSDARG00000101036 (1)
GENE EXPRESSION
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17008 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33738 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH traf2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH traf2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process activation of NF-kappaB-inducing kinase activity (more)
    Cellular Component cytoplasm (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA traf2b-202 (1)    Ensembl 2135
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM traf2b No data available
    MARKER RELATIONSHIPS
    traf2b Contained in: [BAC] DKEY-170O10 (1) (order this)
    traf2b Encodes: [EST] fd14c07
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_005165499 (1)
    Genomic GenBank:BX294186 (1) 143396 nt
    Select Tool
    Polypeptide UniProtKB:A0A286YAJ9 (1) 545 aa
    Sequence Information (all 17)
    ORTHOLOGY for traf2b ( Chr: 5 )
    CITATIONS (25)