Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-5286
Gene Name: polymerase (RNA) I polypeptide A
Gene Symbol: polr1a
Previous Names: fa26a03, sb:cb935, wu:fa26a03
Location: Chr: 14   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (12 images) from Thisse et al., 2001 [cb935]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
  alar plate midbrain region, cerebellum, eye, gut (all 15) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 7 genotypes
Alleles: hi3639Tg, la012505Tg, sa12570, sa1376, sa2745
PHENOTYPE
Data: 4 figures from 4 publications
Observed in: blood, brain, central nervous system, extension (all 15) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process transcription, DNA-templated (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000722 (1)
  • InterPro:IPR006592 (1)
  • InterPro:IPR007066 (1)
  • InterPro:IPR007080 (1)
  • InterPro:IPR007081 (1)
  • InterPro:IPR007083 (1)
  • InterPro:IPR015699 (1)
  • Pfam:PF00623 (1)
  • Pfam:PF04983 (1)
  • Pfam:PF04997 (1)
  • Pfam:PF04998 (1)
  • Pfam:PF05000 (1)
  • EC:2.7.7.6 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA polr1a-001 (1) 5286
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM polr1a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    polr1a Contained in: [BAC] CH73-87E17 (1) (order this), CH211-2M15 (1) (order this)
    polr1a Encodes: [EST] cb935 (1) (order this), fa26a03
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_001922804 (1) 5457 bp
    Genomic GenBank:AL929267 (1) 175892 bp
    Select Tool
    Polypeptide UniProtKB:E7F710 (1) 1710 aa
    Sequence Clusters UniGene:12641 (1)
    Sequence Information (all 31)
    OTHER polr1a GENE PAGES
  • Gene:327078 (1)
  • VEGA:OTTDARG00000020893 (1)
  • Ensembl(Zv9):ENSDARG00000029172 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish polr1a 14  
    Human POLR1A 2 (2p11.2)
  • Gene:25885
  • Mouse Polr1a 6 ( 32.21 cM)
  • MGI:1096397
  • Gene:20019
  • Orthology Details
    CITATIONS (26)