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ZIRC
ZFIN ID: ZDB-GENE-030131-5274
Gene Name: annexin A1c
Gene Symbol: anxa1c    Nomenclature History

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Previous Names: sb:cb276, wu:fa22e03, wu:fj17g03, zgc:123146

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have several functions, including calcium-dependent phospholipid binding activity; phospholipase A2 inhibitor activity; and protein binding activity, bridging. Predicted to be involved in several processes, including animal organ development; regulation of T cell activation; and regulation of secretion by cell. Predicted to localize to the extracellular space and plasma membrane. Human ortholog(s) of this gene implicated in brain ischemia and pancreatic cancer. Is expressed in EVL and periderm. Orthologous to human ANXA1 (annexin A1).
Genome Resources: Alliance (1),  Gene:494158 (1),  Ensembl(GRCz11):ENSDARG00000104359 (1)
GENE EXPRESSION
All Expression Data: 6 figures from 3 publications
Directly Submitted Expression Data: 4 figures (5 images) from Thisse et al., 2001 [cb276]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1750 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12045 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa18826 Point Mutation Unknown Premature Stop ENU
    sa25318 Point Mutation Unknown Splice Site ENU
    sa38522 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH anxa1c HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH anxa1c VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin cytoskeleton reorganization (more)
    Cellular Component extracellular space (more)
    Molecular Function calcium-dependent phospholipid binding (more)
    GO Terms (all 48)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA anxa1c-201 (1)    Ensembl 871
    anxa1c-202 (1)    Ensembl 1031
    anxa1c-203 (1)    Ensembl 1175
    ncRNA anxa1c-004 (1)    Ensembl 713
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM anxa1c No data available
    MARKER RELATIONSHIPS
    anxa1c Contained in: [BAC] CH73-348L8 (1) (order this)
    anxa1c Contains: [SNP] rs3727923 (1), rs3727924 (1), rs3727925 (1), rs3727926 (1)
    anxa1c Encodes: [EST] fa22e03, fj17g03
    [cDNA] MGC:123146 (1) (order this)
    anxa1c Has Artifact: [cDNA] MGC:86853 (1) (order this)
    anxa1c Is Hybridized by: [EST] cb276 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_181760 (1) 1188 bp
    Genomic GenBank:CU570890 (1) 82299 bp
    Select Tool
    Polypeptide UniProtKB:Q804H0 (1) 341 aa
    Sequence Clusters UniGene:1190 (1)
    Sequence Information (all 18)
    ORTHOLOGY for anxa1c ( Chr: 5 )
    CITATIONS (27)