ZFIN ID: ZDB-GENE-030131-5237
Gene Name: capping actin protein of muscle Z-line subunit alpha 1a
Gene Symbol: capza1a    Nomenclature History

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Previous Names: capza1, wu:fa19e05, wu:fk22d04, zgc:56314, zgc:85654

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity. Predicted to be involved in actin cytoskeleton organization and barbed-end actin filament capping. Localizes to Z disc. Orthologous to several human genes including CAPZA1 (capping actin protein of muscle Z-line subunit alpha 1).
Genome Resources: Alliance (1),  Gene:327029 (1),  Ensembl(GRCz11):ENSDARG00000034240 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56314]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa33958 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH capza1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH capza1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin filament capping (more)
    Cellular Component Z disc (more)
    Molecular Function actin binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA capza1a-202 (1)    Ensembl 75
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM capza1a No data available
    MARKER RELATIONSHIPS
    capza1a Contained in: [BAC] CH73-126M5 (1)
    capza1a Encodes: [EST] fa19e05, fk22d04 (1)
    [cDNA] MGC:56314 (1), MGC:85654 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212697 (1) 1796 nt
    Genomic GenBank:CU469362 (1) 137417 nt
    Select Tool
    Polypeptide UniProtKB:Q6NWK1 (1) 286 aa
    Sequence Information (all 18)
    ORTHOLOGY for capza1a ( Chr: 6 )
    CITATIONS (24)