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Gene

mrm2

ID
ZDB-GENE-030131-5205
Name
mitochondrial rRNA methyltransferase 2
Symbol
mrm2 Nomenclature History
Previous Names
  • ftsj2 (1)
  • si:dkey-72a22.3
  • wu:fa18a02
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to enable rRNA (uridine-2'-O-)-methyltransferase activity. Predicted to be involved in RNA methylation. Predicted to act upstream of or within methylation. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome. Orthologous to human MRM2 (mitochondrial rRNA methyltransferase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mrm2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Mitochondrial DNA depletion syndrome 17 618567
Associated With mrm2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002877 Ribosomal RNA methyltransferase FtsJ domain
Family IPR015507 Ribosomal RNA large subunit methyltransferase E
Homologous_superfamily IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
Domain Details Per Protein
Protein Length Ribosomal RNA large subunit methyltransferase E Ribosomal RNA methyltransferase FtsJ domain S-adenosyl-L-methionine-dependent methyltransferase
UniProtKB:X1WFE4 259
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations