Gene

sgsh

ID
ZDB-GENE-030131-4958
Name
N-sulfoglucosamine sulfohydrolase (sulfamidase)
Symbol
sgsh Nomenclature History
Previous Names
  • wu:fe14h11
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have N-acetylglucosamine-6-sulfatase activity; N-sulfoglucosamine sulfohydrolase activity; and glycosaminoglycan binding activity. Predicted to be involved in glycosaminoglycan catabolic process and heparan sulfate proteoglycan catabolic process. Human ortholog(s) of this gene implicated in mucopolysaccharidosis III and mucopolysaccharidosis type IIIA. Orthologous to human SGSH (N-sulfoglucosamine sulfohydrolase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sgsh Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
mucopolysaccharidosis type IIIA Alliance Mucopolysaccharidosis type IIIA (Sanfilippo A) 252900
Associated With sgsh Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR024607 Sulfatase, conserved site
Domain IPR000917 Sulfatase, N-terminal
Homologous_superfamily IPR017850 Alkaline-phosphatase-like, core domain superfamily
Domain Details Per Protein
Protein Length Alkaline-phosphatase-like, core domain superfamily Sulfatase, conserved site Sulfatase, N-terminal
UniProtKB:B0V3V9 511
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations