Gene

acsl3b

ID

ZDB-GENE-030131-492

Name

acyl-CoA synthetase long chain family member 3b

Symbol

acsl3b Nomenclature History

Previous Names

acsl3
fa07a08
im:7155129 (1)
si:dkey-20f20.5 (1)
wu:fa07a08 (1)
wu:fb34c03 (1)

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process; long-chain fatty-acyl-CoA metabolic process; and neuron differentiation. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum; lipid droplet; and plasma membrane. Is expressed in several structures, including digestive system; eye; gill; heart; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in asthma; breast cancer; and prostate cancer. Orthologous to human ACSL3 (acyl-CoA synthetase long chain family member 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7155129 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With acsl3b Human Ortholog

No data available

Associated With acsl3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020845	AMP-binding, conserved site
Domain	IPR000873	AMP-dependent synthetase/ligase
Domain	IPR025110	AMP-binding enzyme, C-terminal domain
Homologous_superfamily	IPR042099	ANL, N-terminal domain
Homologous_superfamily	IPR045851	AMP-binding enzyme, C-terminal domain superfamily