ZFIN ID: ZDB-GENE-030131-492
Gene Name: acyl-CoA synthetase long chain family member 3b
Gene Symbol: acsl3b    Nomenclature History

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Previous Names: acsl3, fa07a08, im:7155129 (1), si:dkey-20f20.5 (1), wu:fa07a08 (1), wu:fb34c03 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process; long-chain fatty-acyl-CoA metabolic process; and neuron differentiation. Predicted to localize to endoplasmic reticulum; lipid droplet; and plasma membrane. Is expressed in several structures, including digestive system; eye; gill; heart; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in asthma; breast cancer; and prostate cancer. Orthologous to human ACSL3 (acyl-CoA synthetase long chain family member 3).
Genome Resources: Alliance (1),  Gene:559656 (1),  Ensembl(GRCz11):ENSDARG00000014674 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7155129]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2049 Point Mutation Unknown Splice Site ENU
sa15610 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39930 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH acsl3b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH acsl3b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process long-chain fatty acid metabolic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA acsl3b-202 (1)    Ensembl 5022
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM acsl3b No data available
    MARKER RELATIONSHIPS
    acsl3b Contained in: [BAC] DKEY-20F20 (1) (order this)
    acsl3b Encodes: [EST] fa07a08, fb34c03, IMAGE:7155129 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001145932 (1)
    Genomic GenBank:BX085193 (1) 246911 nt Blast at MegaBLAST
    Polypeptide UniProtKB:B0S5C4 (1) 711 aa
    Sequence Information (all 19)
    ORTHOLOGY for acsl3b ( Chr: 2 )
    CITATIONS (26)