Gene
zgc:56622
- ID
- ZDB-GENE-030131-4758
- Name
- zgc:56622
- Symbol
- zgc:56622 Nomenclature History
- Previous Names
-
- fd58h08
- wu:fd58h08
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable aldose reductase (NADPH) activity. Predicted to be involved in glucose homeostasis. Predicted to be located in apical plasma membrane. Predicted to be active in cytosol. Is expressed in intestinal bulb. Human ortholog(s) of this gene implicated in 46,XY sex reversal 8; B-lymphoblastic leukemia/lymphoma; T-cell acute lymphoblastic leukemia; alcohol dependence; and leukemia. Orthologous to human AKR1C1 (aldo-keto reductase family 1 member C1); AKR1C2 (aldo-keto reductase family 1 member C2); and AKR1C3 (aldo-keto reductase family 1 member C3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56622 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Aldo-keto reductase | Aldo/keto reductase, conserved site | NADP-dependent oxidoreductase domain | NADP-dependent oxidoreductase domain superfamily |
---|---|---|---|---|---|---|
UniProtKB:Q7ZWA4 | InterPro | 289 | ||||
UniProtKB:A0A8M2BH91 | InterPro | 324 | ||||
UniProtKB:A0A8M1PA35 | InterPro | 324 |
- Genome Browsers
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
zgc:56622-201
(1)
|
Ensembl | 1,511 nt |
Interactions and Pathways
No data available
Plasmids
No data available