ZFIN ID: ZDB-GENE-030131-4755
Gene Name: solute carrier family 6 member 19b
Gene Symbol: slc6a19b    Nomenclature History

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Previous Names: slc6a19, wu:fd58f10, zgc:66050 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have neutral amino acid transmembrane transporter activity. Predicted to localize to the plasma membrane. Human ortholog(s) of this gene implicated in Hartnup disease. Is expressed in floor plate; pronephric duct; and yolk syncytial layer. Orthologous to human SLC6A19 (solute carrier family 6 member 19).
Genome Resources: Alliance (1),  Gene:326030 (1),  Ensembl(GRCz11):ENSDARG00000056719 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (8 images) from Thisse et al., 2004 [MGC:66050]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH slc6a19b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Hartnup disease Alliance Hartnup disorder 234500
Hyperglycinuria 138500
Iminoglycinuria, digenic 242600
DISEASE ASSOCIATED WITH slc6a19b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process amino acid transmembrane transport (more)
Cellular Component integral component of membrane (more)
Molecular Function neurotransmitter:sodium symporter activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Family IPR000175 Sodium:neurotransmitter symporter
Homologous_superfamily IPR037272 Sodium:neurotransmitter symporter superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA slc6a19b-201 (1)    Ensembl 2538
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM slc6a19b No data available
MARKER RELATIONSHIPS
slc6a19b Contained in: [BAC] CH211-209D1 (1), CH211-254P10 (1)
slc6a19b Encodes: [EST] fd58f10
[cDNA] MGC:66050 (1), MGC:174494 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_199736 (1) 2580 bp
Genomic GenBank:CT027610 (1) 279933 bp Blast at MegaBLAST
Polypeptide UniProtKB:A8KC13 (1) 651 aa
Sequence Information (all 16)
ORTHOLOGY for slc6a19b ( Chr: 16 )
CITATIONS (24)