Gene

habp2

ID
ZDB-GENE-030131-4721
Name
hyaluronan binding protein 2
Symbol
habp2 Nomenclature History
Previous Names
  • fd56a04
  • wu:fd56a04 (1)
  • zgc:171352
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to extracellular space. Is expressed in liver. Human ortholog(s) of this gene implicated in thrombophilia due to thrombin defect and thyroid gland papillary carcinoma. Orthologous to human HABP2 (hyaluronan binding protein 2).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With habp2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
prothrombin thrombophilia Alliance {Venous thromboembolism, susceptibility to} 188050
thrombophilia due to thrombin defect Alliance {Venous thromboembolism, susceptibility to} 188050
{?Thyroid cancer, nonmedullary, 5} 616535
Associated With habp2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR018114 Serine proteases, trypsin family, histidine active site
Active_site IPR033116 Serine proteases, trypsin family, serine active site
Conserved_site IPR018056 Kringle, conserved site
Domain IPR000001 Kringle
Domain IPR000742 EGF-like domain
Domain IPR001254 Serine proteases, trypsin domain
Domain IPR001881 EGF-like calcium-binding domain
Family IPR001314 Peptidase S1A, chymotrypsin family
Family IPR012224 Peptidase S1A, coagulation factor VII/IX/X/C/Z
Homologous_superfamily IPR009003 Peptidase S1, PA clan
Homologous_superfamily IPR013806 Kringle-like fold
Homologous_superfamily IPR038178 Kringle superfamily
Homologous_superfamily IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
Domain Details Per Protein
Protein Length EGF-like calcium-binding domain EGF-like domain Kringle Kringle, conserved site Kringle-like fold Kringle superfamily Peptidase S1A, chymotrypsin family Peptidase S1A, coagulation factor VII/IX/X/C/Z Peptidase S1, PA clan Peptidase S1, PA clan, chymotrypsin-like fold Serine proteases, trypsin domain Serine proteases, trypsin family, histidine active site Serine proteases, trypsin family, serine active site
UniProtKB:Q08CS9 558
UniProtKB:A8WFR8 497
UniProtKB:A3KP18 558
UniProtKB:Q502D2 548
UniProtKB:Q1JQ29 552
UniProtKB:F1QW52 546
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations