Gene

plxna4

ID
ZDB-GENE-030131-4663
Name
plexin A4
Symbol
plxna4 Nomenclature History
Previous Names
  • wu:fd49b01
  • wu:fe15f03
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Is predicted to enable semaphorin receptor activity. Involved in several processes, including generation of neurons; regulation of GTPase activity; and regulation of cell shape. Acts upstream of or within axon guidance; axonal defasciculation; and morphogenesis of a branching structure. Predicted to be integral component of membrane. Predicted to be part of semaphorin receptor complex. Is expressed in several structures, including basal plate midbrain region; nervous system; optic vesicle; presumptive neural retina; and trigeminal placode. Orthologous to human PLXNA4 (plexin A4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
23 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from van der Klaauw et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With plxna4 Human Ortholog
No data available
Associated With plxna4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001627 Sema domain
Domain IPR002909 IPT domain
Domain IPR013548 Plexin, cytoplasmic RasGAP domain
Domain IPR016201 PSI domain
Domain IPR041019 Plexin, TIG domain 1
Domain IPR041362 Plexin, TIG domain 2
Family IPR031148 Plexin family
Homologous_superfamily IPR008936 Rho GTPase activation protein
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR014756 Immunoglobulin E-set
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036352 Sema domain superfamily
Repeat IPR002165 Plexin repeat
Domain Details Per Protein
Protein Length Immunoglobulin E-set Immunoglobulin-like fold IPT domain Plexin, cytoplasmic RasGAP domain Plexin family Plexin repeat Plexin, TIG domain 1 Plexin, TIG domain 2 PSI domain Rho GTPase activation protein Sema domain Sema domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q90ZG5 93
UniProtKB:Q6BEA0 1903
UniProtKB:B3DK42 1903
UniProtKB:T1ECS6 1903
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations