ZFIN ID: ZDB-GENE-030131-4652
Gene Name: nuclear receptor subfamily 5, group A, member 5
Gene Symbol: nr5a5    Nomenclature History

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Previous Names: fd46g06, ff1c (2), wu:fd46g06, zgc:111842, zgc:153866 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Exhibits DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in hormone-mediated signaling pathway; positive regulation of transcription by RNA polymerase II; and tissue development. Predicted to localize to RNA polymerase II transcription regulator complex. Is expressed in several structures, including digestive system; fin; gill; heart; and pleuroperitoneal region. Orthologous to human NR5A2 (nuclear receptor subfamily 5 group A member 2).
Genome Resources: Alliance (1),  Gene:407626 (1),  Ensembl(GRCz11):ENSDARG00000039116 (2)
GENE EXPRESSION
All Expression Data: 10 figures from 3 publications
Directly Submitted Expression Data: 7 figures (2 images) from Thisse et al., 2008 [af327373]
Wild-type Stages, Structures: Larval:Day 4 (96.0h-120.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa11774 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33319 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nr5a5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nr5a5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component host cell nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nr5a5-201 (1)    Ensembl 2049
    nr5a5-202 (1)    Ensembl 1748
    nr5a5-203 (1)    Ensembl 765
    ncRNA nr5a5-003 (1)    Ensembl 758
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nr5a5 No data available
    MARKER RELATIONSHIPS
    nr5a5 Contained in: [BAC] DKEYP-39A12 (1)
    nr5a5 Encodes: [EST] af327373 (1), fd46g06
    [cDNA] MGC:111842 (1), MGC:153866 (1), MGC:195336 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001077272 (1) 2081 nt
    Genomic GenBank:CR933758 (1) 188461 nt
    Select Tool
    Polypeptide UniProtKB:B3DKN2 (1) 537 aa
    Sequence Information (all 30)
    ORTHOLOGY for nr5a5 ( Chr: 3 )
    CITATIONS (35)