ZFIN ID: ZDB-GENE-030131-464
Gene Name: WD repeat domain 36
Gene Symbol: wdr36    Nomenclature History

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Previous Names: TA-WDRP-like (1), wu:fb33e10, zgc:66324

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Involved in rRNA processing. Localizes to cytoplasm and nucleolus. Is expressed in digestive system; heart; immature eye; nervous system; and somite. Human ortholog(s) of this gene implicated in glaucoma and primary open angle glaucoma. Orthologous to human WDR36 (WD repeat domain 36).
Genome Resources: Alliance (1),  Gene:321745 (1),  Ensembl(GRCz11):ENSDARG00000004774 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7138943]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi3630aTg Transgenic Insertion 5' UTR Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la025179Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14176 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33722 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-wdr36 N/A 1
    MO2-wdr36 N/A 1
    DISEASE ASSOCIATED WITH wdr36 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    open-angle glaucoma Alliance Glaucoma 1, open angle, G 609887
    DISEASE ASSOCIATED WITH wdr36 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process rRNA processing (more)
    Cellular Component cytoplasm (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA wdr36-201 (1)    Ensembl 2917
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM wdr36 No data available
    MARKER RELATIONSHIPS
    wdr36 Contained in: [BAC] CH211-220B11 (1)
    wdr36 Encodes: [EST] fb33e10, IMAGE:7138943 (1)
    [cDNA] MGC:66324 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001308831 (1)
    Genomic GenBank:BX294395 (1) 213232 nt Blast at MegaBLAST
    Polypeptide UniProtKB:B5DDC5 (1) 904 aa
    Sequence Information (all 18)
    ORTHOLOGY for wdr36 ( Chr: 5 )
    CITATIONS (31)