ZFIN ID: ZDB-GENE-030131-4532
Gene Name: chromodomain helicase DNA binding protein 4b
Gene Symbol: chd4b    Nomenclature History

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Previous Names: si:ch211-57k11.10, wu:fb44b12, wu:fd12d03 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and metal ion binding activity. Predicted to localize to nucleus. Is expressed in blastomere and central nervous system. Orthologous to human CHD4 (chromodomain helicase DNA binding protein 4).
Genome Resources: Alliance (1),  Gene:560622 (1),  Ensembl(GRCz11):ENSDARG00000025789 (2)
GENE EXPRESSION
All Expression Data: 2 figures from Pfefferli et al., 2014
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13914 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16797 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-chd4b
    1
    CRISPR2-chd4b
    1
    MO1-chd4b N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH chd4b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Sifrim-Hitz-Weiss syndrome 617159
    DISEASE ASSOCIATED WITH chd4b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component nucleus (more)
    Molecular Function ATP binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA chd4b-201 (1)    Ensembl 7365
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM chd4b No data available
    MARKER RELATIONSHIPS
    chd4b Contained in: [BAC] CH211-57K11 (1)
    chd4b Encodes: [EST] fb44b12 (1), fd12d03
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_680607 (1) 7406 nt
    Genomic GenBank:BX511250 (1) 189081 nt
    Select Tool
    Polypeptide UniProtKB:F1RBT2 (1) 1953 aa
    Sequence Information (all 34)
    ORTHOLOGY for chd4b ( Chr: 16 )
    CITATIONS (26)