Gene

sh3gl1a

ID
ZDB-GENE-030131-4524
Name
SH3-domain GRB2-like 1a
Symbol
sh3gl1a Nomenclature History
Previous Names
  • eenb (1)
  • wu:fd12b05
  • wu:fy33c10
  • zgc:56637
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in acute myeloid leukemia and malignant glioma. Is expressed in several structures, including EVL; digestive system; epidermis; hatching gland; and periderm. Orthologous to human SH3GL1 (SH3 domain containing GRB2 like 1, endophilin A2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sh3gl1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
acute myeloid leukemia Alliance Leukemia, acute myeloid 601626
Associated With sh3gl1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001452 SH3 domain
Domain IPR004148 BAR domain
Domain IPR035824 Endophilin-A, SH3 domain
Family IPR028501 Endophilin-A
Homologous_superfamily IPR027267 AH/BAR domain superfamily
Homologous_superfamily IPR036028 SH3-like domain superfamily
Domain Details Per Protein
Protein Length AH/BAR domain superfamily BAR domain Endophilin-A Endophilin-A, SH3 domain SH3 domain SH3-like domain superfamily
UniProtKB:Q7ZWA0 365
UniProtKB:Q1MT71 365
UniProtKB:A0A2R8QAF3 351
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations