ZFIN ID: ZDB-GENE-030131-4473
Gene Name: calcium/calmodulin-dependent serine protein kinase b
Gene Symbol: caskb    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: fd08c05, wu:fd08c05

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and protein kinase activity. Predicted to be involved in protein phosphorylation. Human ortholog(s) of this gene implicated in FG syndrome and syndromic X-linked intellectual disability Najm type. Orthologous to human CASK (calcium/calmodulin dependent serine protein kinase).
Genome Resources: Alliance (1),  Gene:100148073 (1),  Ensembl(GRCz11):ENSDARG00000100119 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa38586 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-caskb N/A 1
    DISEASE ASSOCIATED WITH caskb HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    FG syndrome Alliance FG syndrome 4 300422
    Mental retardation, with or without nystagmus 300422
    syndromic X-linked intellectual disability Najm type Alliance Mental retardation and microcephaly with pontine and cerebellar hypoplasia 300749
    DISEASE ASSOCIATED WITH caskb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein phosphorylation (more)
    Molecular Function ATP binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA caskb-202 (1)    Ensembl 1510
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM caskb No data available
    MARKER RELATIONSHIPS
    caskb Contained in: [Fosmid] CH1073-202I10 (1)
    caskb Encodes: [EST] fd08c05
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001142376 (1)
    Genomic GenBank:CU914788 (1) 30362 nt
    Select Tool
    Polypeptide UniProtKB:B6EUL7 (1) 921 aa
    Sequence Information (all 28)
    ORTHOLOGY for caskb ( Chr: 6 )
    CITATIONS (13)