Gene

arid1b

ID
ZDB-GENE-030131-4459
Name
AT rich interactive domain 1B (SWI1-like)
Symbol
arid1b Nomenclature History
Previous Names
  • fd07d11
  • si:dkey-60a16.3
  • wu:fd07d11
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to enable DNA binding activity. Predicted to contribute to nucleosome binding activity. Predicted to be involved in positive regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin remodeling. Predicted to be located in nucleus. Predicted to be part of SWI/SNF complex and nBAF complex. Predicted to be active in nucleoplasm. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome; Coffin-Siris syndrome 1; intellectual disability; lung non-small cell carcinoma; and neuroblastoma. Orthologous to human ARID1B (AT-rich interaction domain 1B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arid1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Coffin-Siris syndrome 1 Alliance Coffin-Siris syndrome 1 135900
Associated With arid1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001606 ARID DNA-binding domain
Domain IPR033388 SWI/SNF-like complex subunit BAF250, C-terminal
Family IPR021906 SWI/SNF-like complex subunit BAF250/Osa
Family IPR038040 AT-rich interactive domain-containing protein 1B
Homologous_superfamily IPR011989 Armadillo-like helical
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR036431 ARID DNA-binding domain superfamily
Domain Details Per Protein
Protein Length ARID DNA-binding domain ARID DNA-binding domain superfamily Armadillo-like helical Armadillo-type fold AT-rich interactive domain-containing protein 1B SWI/SNF-like complex subunit BAF250, C-terminal SWI/SNF-like complex subunit BAF250/Osa
UniProtKB:G8FUX7 1840
UniProtKB:Q5RGW7 2121
UniProtKB:A0A2R8RJE4 2081
UniProtKB:A0A0R4ISW4 2122
UniProtKB:G8FUX6 1840
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations