ZFIN ID: ZDB-GENE-030131-4433
Gene Name: protein phosphatase 4, catalytic subunit a
Gene Symbol: ppp4ca    Nomenclature History

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Previous Names: ppp4c (1), wu:fd05e08, zgc:56413

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have metal ion binding activity and phosphoprotein phosphatase activity. Involved in angiogenesis; central nervous system development; and determination of ventral identity. Predicted to localize to cytoplasm and microtubule organizing center. Is expressed in blastoderm; brain; and head. Orthologous to human PPP4C (protein phosphatase 4 catalytic subunit).
Genome Resources: Alliance (1),  Gene:100003080 (1),  Ensembl(GRCz11):ENSDARG00000070570 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56413]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la024060Tg Transgenic Insertion Unknown Unknown DNA
la028886Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33179 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ppp4ca N/A 1
    MO2-ppp4ca N/A 1
    MO3-ppp4ca N/A 1
    MO4-ppp4ca N/A 1
    MO5-ppp4ca N/A 2
    MO6-ppp4ca N/A 2
    DISEASE ASSOCIATED WITH ppp4ca HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ppp4ca VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Cellular Component cytoplasm (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ppp4ca-201 (1)    Ensembl 1822
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ppp4ca No data available
    MARKER RELATIONSHIPS
    ppp4ca Contained in: [BAC] CH73-33I10 (1)
    ppp4ca Encodes: [EST] fd05e08
    [cDNA] MGC:56413 (1), MGC:174832 (1), MGC:198422 (1), MGC:198424 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001110414 (1) 1533 nt
    Genomic GenBank:BX511232 (1) 171843 nt
    Select Tool
    Polypeptide UniProtKB:A8WGP3 (1) 311 aa
    Sequence Information (all 24)
    ORTHOLOGY for ppp4ca ( Chr: 3 )
    CITATIONS (34)