ZFIN ID: ZDB-GENE-030131-441
Gene Name: junctional adhesion molecule 3b
Gene Symbol: jam3b    Nomenclature History

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Previous Names: jam3, jamc.1 (1), jamc (1), sr:nyz155, wu:fb30h11 (1), wu:fc08c06 (1), wu:fc13e04 (1), wu:fc25g11 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have protein heterodimerization activity and protein homodimerization activity. Involved in myoblast fusion. Predicted to localize to several cellular components, including bicellular tight junction; desmosome; and integral component of membrane. Is expressed in several structures, including cranium; musculature system; myoblast; nervous system; and somite. Orthologous to human JAM3 (junctional adhesion molecule 3).
Genome Resources: Alliance (1),  Gene:569217 (1),  Ensembl(GRCz11):ENSDARG00000061794 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa37 Point Mutation Unknown Missense ENU
sa14980 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16151 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tpl7Gt Transgenic Insertion Unknown Unknown DNA
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-jam3b N/A 2
    MO2-jam3b N/A 1
    DISEASE ASSOCIATED WITH jam3b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Hemorrhagic destruction of the brain, subependymal calcification, and cataracts 613730
    DISEASE ASSOCIATED WITH jam3b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process myoblast fusion (more)
    Cellular Component bicellular tight junction (more)
    Molecular Function protein binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA jam3b-201 (1)    Ensembl 4865
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM jam3b No data available
    MARKER RELATIONSHIPS
    jam3b Contained in: [BAC] CH211-8G12 (1), DKEY-106J17 (1) (order this)
    jam3b Contains: [SNP] rs3728175 (1), rs3729118 (1), rs3729401 (1), rs3729449 (1), rs3729450 (1)
    jam3b Encodes: [EST] fb30h11, fc08c06, fc13e04, fc25g11, nyz155
    [cDNA] cssl:d123 (1), cssl:d178 (1), MGC:163100 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001082863 (1) 1793 nt
    Genomic GenBank:BX470244 (1) 200867 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1QYD7 (1) 333 aa
    Sequence Information (all 26)
    ORTHOLOGY for jam3b ( Chr: 21 )
    CITATIONS (41)