Gene

rpl27

ID

ZDB-GENE-030131-4343

Name

ribosomal protein L27

Symbol

rpl27 Nomenclature History

Previous Names

fc93a08
wu:fc93a08
zgc:56171 (1)

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to be a structural constituent of ribosome. Involved in erythrocyte differentiation. Predicted to localize to cytoplasmic side of rough endoplasmic reticulum membrane and cytosolic large ribosomal subunit. Is expressed in endodermal cell; intestine; liver; and pancreas. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 16. Orthologous to human RPL27 (ribosomal protein L27).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

Thisse Expression Data

MGC:56171 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Wang et al., 2015
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rpl27 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Diamond-Blackfan anemia 16	Alliance	?Diamond-Blackfan anemia 16	617408

Associated With rpl27 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018262	Ribosomal protein L27e, conserved site
Domain	IPR005824	KOW
Domain	IPR041991	Eukaryotic Ribosomal Protein L27, KOW domain
Family	IPR001141	Ribosomal protein L27e
Homologous_superfamily	IPR008991	Translation protein SH3-like domain superfamily
Homologous_superfamily	IPR038655	Ribosomal protein L27e superfamily

Domain Details Per Protein

Protein	Length	Eukaryotic Ribosomal Protein L27, KOW domain	KOW	Ribosomal protein L27e	Ribosomal protein L27e, conserved site	Ribosomal protein L27e superfamily	Translation protein SH3-like domain superfamily
UniProtKB:Q7ZV82 InterPro	136
UniProtKB:B2GP62 InterPro	136

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
mRNA	rpl27-201 (1) Ensembl	487 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	rpl27-202 (1) Ensembl	682 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

SignaFish

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations