ZFIN ID: ZDB-GENE-030131-4317
Gene Name: COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
Gene Symbol: cops4    Nomenclature History

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Previous Names: fc90c08, wu:fc90c08, zgc:77137

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to contribute to NEDD8-specific protease activity. Predicted to localize to COP9 signalosome and cytosol. Is expressed in liver. Orthologous to human COPS4 (COP9 signalosome subunit 4).
Genome Resources: Alliance (1),  Gene:325592 (1),  Ensembl(GRCz11):ENSDARG00000043732 (2)
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2004 [MGC:77137]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa215 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa27571 Point Mutation Unknown Premature Stop ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cops4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cops4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component cell junction (more)
    Molecular Function CONTRIBUTES_TO   NEDD8-specific protease activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cops4-201 (1)    Ensembl 1789
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cops4 No data available
    MARKER RELATIONSHIPS
    cops4 Contained in: [BAC] CH211-126I22 (1)
    cops4 Encodes: [EST] fc90c08
    [cDNA] MGC:77137 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_205556 (1) 1333 nt
    Genomic GenBank:BX510369 (1) 168142 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8QL66 (1) 407 aa
    Sequence Information (all 16)
    ORTHOLOGY for cops4 ( Chr: 10 )
    CITATIONS (24)