ZFIN ID: ZDB-GENE-030131-4120
Gene Name: lysine (K)-specific methyltransferase 2E
Gene Symbol: kmt2e
Previous Names: mll5, wu:fc74b02, zgc:64223
Location: Chr: 4   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:64223]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  central nervous system, intermediate cell mass of mesoderm, unspecified
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-kmt2e (1)

Allele Type Mutagen Suppliers
sa13142 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH kmt2e HUMAN ORTHOLOG No data available
    GENE ONTOLOGY
    Ontology GO Term
    Molecular Function metal ion binding (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001214 (1)
  • InterPro:IPR001965 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR019786 (1)
  • InterPro:IPR019787 (1)
  • PROSITE:PS01359 (1)
  • PROSITE:PS50016 (1)
  • PROSITE:PS50280 (1)
  • Pfam:PF00628 (1)
  • Pfam:PF00856 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA kmt2e-001 (1) 4168
    kmt2e-002 (1) 2704
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM kmt2e No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    kmt2e Contained in: [BAC] DKEY-9A20 (1) (order this), DKEY-63J13 (1) (order this), DKEY-105O6 (1) (order this)
    kmt2e Encodes: [EST] fc74b02
    [cDNA] MGC:64223 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199717 (1) 2608 bp
    Genomic GenBank:BX537162 (1) 223816 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q5TZ08 (1) 1265 aa
    Sequence Clusters UniGene:79417 (1)
    Sequence Information (all 45)
    OTHER kmt2e GENE PAGES
  • Gene:325395 (1)
  • VEGA:OTTDARG00000008335 (1)
  • Ensembl(Zv9):ENSDARG00000007523 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish kmt2e 4  
    Human KMT2E 7 (7q22.1)
  • OMIM:608444
  • Gene:55904
  • Orthology Details
    CITATIONS (18)