Gene

scrt2

ID
ZDB-GENE-030131-4097
Name
scratch family zinc finger 2
Symbol
scrt2 Nomenclature History
Previous Names
  • fc69h09
  • wu:fc69h09
  • zgc:162551
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of DNA damage response, signal transduction by p53 class mediator; regulation of neural precursor cell proliferation; and regulation of neuron apoptotic process. Is expressed in nervous system; spinal cord neural keel; spinal cord neural tube; and trigeminal placode. Orthologous to human SCRT2 (scratch family transcriptional repressor 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With scrt2 Human Ortholog
No data available
Associated With scrt2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Family IPR029794 Transcriptional repressor SCRATCH 1/2
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length Transcriptional repressor SCRATCH 1/2 Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:A4IGB7 312
UniProtKB:Q6YI50 312
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations