ZFIN ID: ZDB-GENE-030131-4097
Gene Name: scratch family zinc finger 2
Gene Symbol: scrt2    Nomenclature History

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Previous Names: fc69h09, wu:fc69h09, zgc:162551

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have DNA binding activity and DNA-binding transcription factor activity. Involved in regulation of DNA damage response, signal transduction by p53 class mediator; regulation of neural precursor cell proliferation; and regulation of neuron apoptotic process. Predicted to localize to the nucleus. Is expressed in nervous system; spinal cord neural keel; spinal cord neural tube; and trigeminal placode. Orthologous to human SCRT2 (scratch family transcriptional repressor 2).
Genome Resources: Alliance (1),  Gene:325372 (1),  Ensembl(GRCz11):ENSDARG00000056175 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-scrt2 N/A 1
MO2-scrt2 N/A 2
DISEASE ASSOCIATED WITH scrt2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH scrt2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of DNA damage response, signal transduction by p53 class mediator (more)
Cellular Component nucleus (more)
Molecular Function metal ion binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Family IPR029794 Transcriptional repressor SCRATCH 1/2
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM scrt2 No data available
MARKER RELATIONSHIPS
scrt2 Encodes: [EST] fc69h09
[cDNA] MGC:162551 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_213637 (1) 2661 bp
Genomic GenBank:CABZ01087202 (1) 36497 bp
Select Tool
Polypeptide UniProtKB:A4IGB7 (1) 312 aa
Sequence Information (all 14)
ORTHOLOGY for scrt2 ( Chr: 8 )
CITATIONS (18)