Gene

nsun2

ID
ZDB-GENE-030131-4017
Name
NOP2/Sun RNA methyltransferase 2
Symbol
nsun2 Nomenclature History
Previous Names
  • wu:fc65a08
  • zgc:55517
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have tRNA (cytosine-5-)-methyltransferase activity and tRNA binding activity. Predicted to be involved in tRNA methylation. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human NSUN2 (NOP2/Sun RNA methyltransferase 2).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nsun2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive non-syndromic intellectual disability Alliance Mental retardation, autosomal recessive 5 611091
Associated With nsun2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type
Family IPR023267 RNA (C5-cytosine) methyltransferase
Family IPR023270 tRNA (C5-cytosine) methyltransferase, NCL1
Homologous_superfamily IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
Domain Details Per Protein
Protein Length RNA (C5-cytosine) methyltransferase S-adenosyl-L-methionine-dependent methyltransferase SAM-dependent methyltransferase RsmB/NOP2-type tRNA (C5-cytosine) methyltransferase, NCL1
UniProtKB:A5PMI3 766
UniProtKB:Q7ZTI1 706
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations