ZFIN ID: ZDB-GENE-030131-4013
Gene Name: oligodendrocyte lineage transcription factor 2
Gene Symbol: olig2    Nomenclature History

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Previous Name: wu:fc64g09

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity and protein dimerization activity. Involved in nervous system development. Is expressed in several structures, including glioblast; nervous system; neural keel; neural plate; and neural tube. Orthologous to human OLIG2 (oligodendrocyte transcription factor 2).
Genome Resources: Alliance (1),  Gene:325288 (1),  Ensembl(GRCz11):ENSDARG00000040946 (2)
GENE EXPRESSION
All Expression Data: 106 figures from 70 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-olig2 N/A 6
MO2-olig2 N/A 1
MO3-olig2 N/A 1
MO4-olig2 N/A 3
MO5-olig2 N/A 1
DISEASE ASSOCIATED WITH olig2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH olig2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process dopaminergic neuron differentiation (more)
Molecular Function DNA-binding transcription factor activity (more)
GO Terms (all 19)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA olig2-201 (1)    Ensembl 1684
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM olig2
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(olig2:DsRed2) olig2 DsRed2 Danio rerio 1 60
Tg(olig2:EGFP) olig2 EGFP Danio rerio 5 137
Tg(olig2:Kaede) olig2 Kaede Danio rerio 1 6
Tg1(olig2:EGFP) olig2 EGFP Danio rerio 1 2
MARKER RELATIONSHIPS
olig2 Contained in: [BAC] CH211-165B19 (1)
olig2 Encodes: [EST] fc64g09, wz12996 (1)
[cDNA] MGC:65727 (1), MGC:76800 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_178100 (1) 1653 nt
Genomic GenBank:BX571724 (1) 174709 nt
Select Tool
Polypeptide UniProtKB:A8WIQ8 (1) 273 aa
Sequence Information (all 21)
ORTHOLOGY for olig2 ( Chr: 9 )
CITATIONS (135)