Gene
gspt1l
- ID
- ZDB-GENE-030131-4009
- Name
- G1 to S phase transition 1, like
- Symbol
- gspt1l Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have GTPase activity and translation release factor activity. Involved in vasculature development. Predicted to localize to translation release factor complex. Is expressed in digestive system; head; hindbrain; proliferative region; and somite. Orthologous to human GSPT1 (G1 to S phase transition 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7139179 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Wang et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR031157 | Tr-type G domain, conserved site |
| Domain | IPR000795 | Translational (tr)-type GTP-binding domain |
| Domain | IPR004160 | Translation elongation factor EFTu/EF1A, C-terminal |
| Domain | IPR004161 | Translation elongation factor EFTu-like, domain 2 |
| Homologous_superfamily | IPR009000 | Translation protein, beta-barrel domain superfamily |
| Homologous_superfamily | IPR009001 | Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | P-loop containing nucleoside triphosphate hydrolase | Translational (tr)-type GTP-binding domain | Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal | Translation elongation factor EFTu/EF1A, C-terminal | Translation elongation factor EFTu-like, domain 2 | Translation protein, beta-barrel domain superfamily | Tr-type G domain, conserved site |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7T358
|
577 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
gspt1l-201
(1)
|
Havana | 2558 nt | |
| mRNA |
gspt1l-202
(1)
|
Havana | 764 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance
- Gene Tree
- Ensembl
- Note
- Woods, et al. (2005. Genome Res. 15:1307-1914.) reported orthology to GSPT1 supported by amino acid sequence identity. Subsequent data supported that a different gene (ZDB-GENE-040822-36) is the ortholog of human GSPT1 based on higher amino acid sequence identity as well as conserved location.