ZFIN ID: ZDB-GENE-030131-4006
Gene Name: lon peptidase 1, mitochondrial
Gene Symbol: lonp1    Nomenclature History

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Previous Names: fc64d11, prss15 (1), wu:fc64d11

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have ATP-dependent peptidase activity and single-stranded DNA binding activity. Predicted to be involved in chaperone-mediated protein complex assembly; mitochondrion organization; and protein quality control for misfolded or incompletely synthesized proteins. Predicted to localize to mitochondrial matrix. Human ortholog(s) of this gene implicated in CODAS syndrome. Orthologous to human LONP1 (lon peptidase 1, mitochondrial).
Genome Resources: Alliance (1),  Gene:563257 (1),  Ensembl(GRCz11):ENSDARG00000102765 (1)
GENE EXPRESSION
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la022151Tg Transgenic Insertion Unknown Unknown DNA
sa39354 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43743 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lonp1 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    CODAS syndrome Alliance CODAS syndrome 600373
    DISEASE ASSOCIATED WITH lonp1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to oxidative stress (more)
    Cellular Component mitochondrion (more)
    Molecular Function ATP binding (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lonp1-201 (1)    Ensembl 4114
    lonp1-202 (1)    Ensembl 741
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lonp1 No data available
    MARKER RELATIONSHIPS
    lonp1 Contained in: [Fosmid] CH1073-188M7 (1), CH1073-288D13 (1)
    lonp1 Encodes: [EST] fc64d11
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_686620 (1)
    Genomic GenBank:CU498832 (1) 39129 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IH79 (1) 966 aa
    Sequence Information (all 13)
    ORTHOLOGY for lonp1 ( Chr: 22 )
    CITATIONS (23)