Gene

aldob

ID
ZDB-GENE-030131-383
Name
aldolase b, fructose-bisphosphate
Symbol
aldob Nomenclature History
Previous Names
  • fb25f09
  • wu:fb25f09
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have fructose-1-phosphate aldolase activity and fructose-bisphosphate aldolase activity. Predicted to be involved in fructose 1,6-bisphosphate metabolic process and glycolytic process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in hereditary fructose intolerance syndrome and type 2 diabetes mellitus. Is expressed in several structures, including EVL; alar plate midbrain region; digestive system; intestinal bulb primordium; and midbrain. Orthologous to human ALDOB (aldolase, fructose-bisphosphate B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
29 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aldob Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hereditary fructose intolerance syndrome Alliance Fructose intolerance, hereditary 229600
Associated With aldob Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR029768 Fructose-bisphosphate aldolase class-I active site
Family IPR000741 Fructose-bisphosphate aldolase, class-I
Homologous_superfamily IPR013785 Aldolase-type TIM barrel
Domain Details Per Protein
Protein Length Aldolase-type TIM barrel Fructose-bisphosphate aldolase, class-I Fructose-bisphosphate aldolase class-I active site
UniProtKB:Q8JH71 364
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations