ZFIN ID: ZDB-GENE-030131-3813
Gene Name: MKS transition zone complex subunit 1
Gene Symbol: mks1
Sequence Ontology ID : SO:0000704

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Previous Names: fc54h05, si:dkey-189h5.2, wu:fc54h05, zgc:153149

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in dorsal convergence; used to study ciliopathy; orthologous to human MKS1 (Meckel syndrome, type 1).
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa7574 Point Mutation Unknown Missense ENU
sa20540 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40567 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • w152 Insertion Unknown Frameshift CRISPR
    Targeting reagents:
    PHENOTYPE
    Data: 3 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH mks1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Bardet-Biedl syndrome 13 Bardet-Biedl syndrome 13 615990
    Joubert syndrome 28 Joubert syndrome 28 617121
    Meckel syndrome 1 Meckel syndrome 1 249000
    DISEASE ASSOCIATED WITH mks1 VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    ciliopathy WT + MO2-mks1 control Tobin et al., 2008
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dorsal convergence (more)
    Molecular Function molecular_function (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR010796 (1)
  • PROSITE:PS51381 (1)
  • Pfam:PF07162 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA mks1-201 (1) 2066
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM mks1 No data available
    MARKER RELATIONSHIPS
    mks1Contained in: [BAC] DKEY-189H5 (1) (order this)
    mks1Encodes: [EST] fc54h05
    [cDNA] MGC:153149 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001077373 (1)
    Genomic GenBank:CR753838 (1) 188660bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8RPF9 (1) 559aa
    Sequence Clusters UniGene:79025 (1)
    Sequence Information (all 14)
    OTHER mks1 GENE PAGES
  • Alliance (1)
  • Gene:556706 (1)
  • VEGA:OTTDARG00000018671 (1)
  • ORTHOLOGY for mks1 (Chr: 5)
    CITATIONS (20)