Gene

hnrnpua

ID
ZDB-GENE-030131-3731
Name
heterogeneous nuclear ribonucleoprotein Ua
Symbol
hnrnpua Nomenclature History
Previous Names
  • fc51c09
  • wu:fc51c09
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have several functions, including basal RNA polymerase II transcription machinery binding activity; nucleic acid binding activity; and promoter-specific chromatin binding activity. Predicted to be involved in RNA localization to chromatin; regulation of nucleobase-containing compound metabolic process; and regulation of organelle organization. Predicted to colocalize with RNA polymerase II transcription regulator complex. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 54. Orthologous to human HNRNPU (heterogeneous nuclear ribonucleoprotein U).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hnrnpua Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
developmental and epileptic encephalopathy 54 Alliance Developmental and epileptic encephalopathy 54 617391
Associated With hnrnpua Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001870 B30.2/SPRY domain
Domain IPR003034 SAP domain
Domain IPR003877 SPRY domain
Domain IPR035778 Heterogeneous nuclear ribonucleoprotein U, SPRY domain
Family IPR026745 Heterogeneous nuclear ribonucleoprotein U
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036361 SAP domain superfamily
Homologous_superfamily IPR043136 B30.2/SPRY domain superfamily
Domain Details Per Protein
Protein Length B30.2/SPRY domain B30.2/SPRY domain superfamily Concanavalin A-like lectin/glucanase domain superfamily Heterogeneous nuclear ribonucleoprotein U Heterogeneous nuclear ribonucleoprotein U, SPRY domain P-loop containing nucleoside triphosphate hydrolase SAP domain SAP domain superfamily SPRY domain
UniProtKB:E7F3J2 760
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations