Gene

cst3

ID
ZDB-GENE-030131-373
Name
cystatin C (amyloid angiopathy and cerebral hemorrhage)
Symbol
cst3 Nomenclature History
Previous Names
  • fb51d07
  • wu:fb24g06
  • wu:fb51d07
  • wu:fc55f03
  • zgc:136227
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have cysteine-type endopeptidase inhibitor activity. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in CST3-related cerebral amyloid angiopathy and age related macular degeneration 11. Orthologous to human CST3 (cystatin C).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cst3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
age related macular degeneration 11 Alliance {Macular degeneration, age-related, 11} 611953
CST3-related cerebral amyloid angiopathy Alliance Cerebral amyloid angiopathy 105150
Associated With cst3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018073 Proteinase inhibitor I25, cystatin, conserved site
Domain IPR000010 Cystatin domain
Domain Details Per Protein
Protein Length Cystatin domain Proteinase inhibitor I25, cystatin, conserved site
UniProtKB:B8A4D0 134
UniProtKB:Q45RG8 128
UniProtKB:B8A4C9 128
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations