Gene

cdc42bpb

ID
ZDB-GENE-030131-3647
Name
CDC42 binding protein kinase beta (DMPK-like)
Symbol
cdc42bpb Nomenclature History
Previous Names
  • si:dkeyp-93h6.2
  • wu:fb98c02 (1)
  • wu:fc48b05 (1)
  • wu:fc90d12 (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Predicted to be involved in actomyosin structure organization and peptidyl-threonine phosphorylation. Predicted to localize to cytoplasm and cytoskeleton. Orthologous to human CDC42BPB (CDC42 binding protein kinase beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdc42bpb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Chilton-Okur-Chung neurodevelopmental syndrome 619841
Associated With cdc42bpb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000095 CRIB domain
Domain IPR000719 Protein kinase domain
Domain IPR000961 AGC-kinase, C-terminal
Domain IPR001180 Citron homology (CNH) domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain IPR014930 Myotonic dystrophy protein kinase, coiled coil
Domain IPR031597 KELK-motif containing domain
Family IPR033232 Serine/threonine-protein kinase MRCK beta
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Protein Length AGC-kinase, C-terminal Citron homology (CNH) domain CRIB domain KELK-motif containing domain Myotonic dystrophy protein kinase, coiled coil PH-like domain superfamily Pleckstrin homology domain Protein kinase, ATP binding site Protein kinase C-like, phorbol ester/diacylglycerol-binding domain Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Serine/threonine-protein kinase MRCK beta
UniProtKB:Q5TZ42 1708
UniProtKB:A0A2R8RNU9 1648
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations