ZFIN ID: ZDB-GENE-030131-3625
Gene Name: LAS1-like, ribosome biogenesis factor
Gene Symbol: las1l
Previous Names: si:dkey-286f3.7, wu:fc47c12, wu:fi05c08
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa674 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-las1l (1), MO2-las1l (1)
    PHENOTYPE
    Data: 2 figures from Butterfield et al., 2014
    Observed in: brain, caudal fin, fast muscle cell, horizontal myoseptum (all 9) expand
    DISEASE ASSOCIATED WITH las1l HUMAN ORTHOLOG No data available
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process chromatin organization (more)
    Cellular Component preribosome, large subunit precursor (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007174 (1)
  • Pfam:PF04031 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA las1l-001 (1) 2642
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM las1l No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    las1lContained in: [BAC] DKEY-286F3 (1) (order this)
    las1lEncodes: [EST] fc47c12, fi05c08
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001126400 (1) 2642bp
    Genomic GenBank:CR812469 (1) 162086bp
    Select Tool
    Polypeptide UniProtKB:A2CF03 (1) 580aa
    Sequence Clusters UniGene:21706 (1)
    Sequence Information (all 26)
    OTHER las1l GENE PAGES 
  • Gene:561321 (1)
  • VEGA:OTTDARG00000017421 (1)
  • Ensembl(GRCz10):ENSDARG00000062457 (1)
  • ORTHOLOGY for las1l (Chr: 5) 
    Species Symbol Chromosome Accession # Evidence
    Human LAS1L X
  • Gene:81887
  • OMIM:300964
  • HGNC:25726
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (2)
    Mouse Las1l X
  • MGI:1923380
  • Gene:76130
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (12)