ZFIN ID: ZDB-GENE-030131-3566
Gene Name: 5'-nucleotidase, cytosolic IIa
Gene Symbol: nt5c2a    Nomenclature History

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Previous Names: nt5c2, fc36f11, sb:eu835, wu:fc36f11, wu:fc45b10

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have 5'-nucleotidase activity. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 45. Orthologous to human NT5C2 (5'-nucleotidase, cytosolic II).
Genome Resources: Alliance (1),  Gene:324845 (1),  Ensembl(GRCz11):ENSDARG00000039399 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu835]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ct103bGt Transgenic Insertion Unknown Unknown DNA
la018514Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa5861 Point Mutation Unknown Premature Stop ENU
    sa17723 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35506 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nt5c2a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    hereditary spastic paraplegia 45 Alliance Spastic paraplegia 45, autosomal recessive 613162
    DISEASE ASSOCIATED WITH nt5c2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Molecular Function metal ion binding (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nt5c2a-202 (1)    Ensembl 3187
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nt5c2a No data available
    MARKER RELATIONSHIPS
    nt5c2a Contained in: [BAC] CH211-67N3 (1)
    nt5c2a Encodes: [EST] eu835 (1), fc36f11, fc45b10
    [cDNA] MGC:56594 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201427 (1) 3204 nt
    Genomic GenBank:AL928951 (1) 183050 nt
    Select Tool
    Polypeptide UniProtKB:E7FC21 (1) 561 aa
    Sequence Information (all 22)
    ORTHOLOGY for nt5c2a ( Chr: 13 )
    CITATIONS (27)