Gene

nt5c2a

ID
ZDB-GENE-030131-3566
Name
5'-nucleotidase, cytosolic IIa
Symbol
nt5c2a Nomenclature History
Previous Names
  • nt5c2
  • fc36f11
  • sb:eu835
  • wu:fc36f11
  • wu:fc45b10
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have 5'-nucleotidase activity. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 45. Orthologous to human NT5C2 (5'-nucleotidase, cytosolic II).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Thisse et al., 2005
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nt5c2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hereditary spastic paraplegia 45 Alliance Spastic paraplegia 45, autosomal recessive 613162
Associated With nt5c2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR008380 HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase
Family IPR016695 Purine 5'-nucleotidase
Homologous_superfamily IPR023214 HAD superfamily
Homologous_superfamily IPR036412 HAD-like superfamily
Domain Details Per Protein
Protein Length HAD-like superfamily HAD superfamily HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase Purine 5'-nucleotidase
UniProtKB:E7FC21 561
UniProtKB:Q7ZWB3 402
UniProtKB:A2ATX6 551
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations