ZFIN ID: ZDB-GENE-030131-3562
Gene Name: copine I
Gene Symbol: cpne1    Nomenclature History

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Previous Names: cpne3, cpne3l, wu:fb69d07, wu:fc45a04

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have calcium-dependent phospholipid binding activity. Predicted to be involved in cellular response to calcium ion; positive regulation of tumor necrosis factor-mediated signaling pathway; and regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to localize to plasma membrane. Is expressed in epidermis; notochord; periderm; polster; and vasculature. Orthologous to human CPNE1 (copine 1).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000075536 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2004 [MGC:55873]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la017806Tg Transgenic Insertion Unknown Unknown DNA
sa44741 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cpne1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cpne1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to calcium ion (more)
    Cellular Component plasma membrane (more)
    Molecular Function calcium-dependent phospholipid binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cpne1-201 (1)    Ensembl 2908
    cpne1-202 (1)    Ensembl 2873
    cpne1-205 (1)    Ensembl 3100
    ncRNA cpne1-003 (1)    Ensembl 572
    cpne1-004 (1)    Ensembl 823
    Browsers: EnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cpne1 No data available
    MARKER RELATIONSHIPS
    cpne1 Contained in: [BAC] CH211-89P16, CH211-134M1
    cpne1 Encodes: [EST] fb69d07 (1), fc45a04
    [cDNA] MGC:55873 (1), MGC:171402 (1), MGC:191833 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA GenBank:BC050240 (1) 2961 nt
    Genomic GenBank:BX950859 (1) 176832 nt
    Select Tool
    Polypeptide UniProtKB:A7MBS0 (1) 534 aa
    Sequence Information (all 17)
    ORTHOLOGY for cpne1 ( Chr: 11 )
    CITATIONS (27)