Community Action Needed: Please respond to the NIH RFI
Gene

gtf2b

ID
ZDB-GENE-030131-3544
Name
general transcription factor IIB
Symbol
gtf2b Nomenclature History
Previous Names
  • wu:fc44c11
  • zgc:66258
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable several functions, including RNA polymerase II core promoter sequence-specific DNA binding activity; RNA polymerase II general transcription initiation factor activity; and TBP-class protein binding activity. Predicted to be involved in RNA polymerase II core complex assembly; protein acetylation; and transcription initiation from RNA polymerase II promoter. Predicted to act upstream of or within transcription preinitiation complex assembly. Predicted to be part of transcription preinitiation complex. Predicted to be active in nucleus. Orthologous to human GTF2B (general transcription factor IIB).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gtf2b Human Ortholog
No data available
Associated With gtf2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR023486 Transcription factor TFIIB, conserved site
Domain IPR013137 Zinc finger, TFIIB-type
Domain IPR013150 Transcription factor TFIIB, cyclin-like domain
Domain IPR013763 Cyclin-like
Family IPR000812 Transcription factor TFIIB
Homologous_superfamily IPR036915 Cyclin-like superfamily
Domain Details Per Protein
Protein Length Cyclin-like Cyclin-like superfamily Transcription factor TFIIB Transcription factor TFIIB, conserved site Transcription factor TFIIB, cyclin-like domain Zinc finger, TFIIB-type
UniProtKB:A0A0R4IRB5 316
UniProtKB:Q7SX98 316
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations