ZFIN ID: ZDB-GENE-030131-333
Gene Name: WD repeat domain 82
Gene Symbol: wdr82    Nomenclature History

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Previous Names: wom, word of mouth, wu:fb22h06 (1), zgc:55453 (1), zgc:85635 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to contribute to histone methyltransferase activity (H3-K4 specific). Predicted to be involved in histone H3-K4 trimethylation. Predicted to localize to the Set1C/COMPASS complex. Orthologous to human WDR82 (WD repeat domain 82).
Genome Resources: Alliance (1),  Gene:321614 (1),  Ensembl(GRCz11):ENSDARG00000014083 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55453]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi2914Tg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1817 Point Mutation Unknown Missense ENU
    sa33933 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-wdr82,twf2a N/A 1
    DISEASE ASSOCIATED WITH wdr82 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH wdr82 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of actin filament polymerization (more)
    Cellular Component nucleus (more)
    Molecular Function actin binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Repeat IPR001680 WD40 repeat
    Domain IPR002108 Actin-depolymerising factor homology domain
    Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
    Domain IPR017986 WD40-repeat-containing domain
    Conserved_site IPR019775 WD40 repeat, conserved site
    Repeat IPR020472 G-protein beta WD-40 repeat
    Family IPR028458 Twinfilin
    Homologous_superfamily IPR029006 ADF-H/Gelsolin-like domain superfamily
    Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
    Family IPR037867 COMPASS component Swd2/WDR82
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA wdr82-201 (1)    Ensembl 2200
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM wdr82 No data available
    MARKER RELATIONSHIPS
    wdr82 Contained in: [BAC] CH211-241N17 (1)
    wdr82 Encodes: [EST] fb22h06
    [cDNA] MGC:55453 (1), MGC:85635, MGC:191278 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199551 (1) 2480 bp
    Genomic GenBank:AL935208 (1) 151406 bp
    Select Tool
    Polypeptide UniProtKB:Q6TEM7 (1) 600 aa
    Sequence Information (all 22)
    ORTHOLOGY for wdr82 ( Chr: 6 )
    CITATIONS (35)