ZFIN ID: ZDB-GENE-030131-330
Gene Name: mitochondrial pyruvate carrier 2b
Gene Symbol: mpc2b    Nomenclature History

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Previous Names: mpc2, brp44, wu:fb22b02, wu:fb22g07, zgc:56391, zgc:86614

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have pyruvate transmembrane transporter activity. Predicted to be involved in mitochondrial pyruvate transmembrane transport. Predicted to localize to integral component of mitochondrial inner membrane. Is expressed in several structures, including alar plate midbrain region; digestive system; eye; optic tectum; and pectoral fin. Orthologous to human MPC2 (mitochondrial pyruvate carrier 2).
Genome Resources: Alliance (1),  Gene:321611 (1),  Ensembl(GRCz11):ENSDARG00000024478 (2)
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 4 figures (6 images) from Thisse et al., 2004 [MGC:56391]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Larval:Day 4 (96.0h-120.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la029586Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-mpc2b N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mpc2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mpc2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mitochondrial pyruvate transmembrane transport (more)
    Cellular Component membrane (more)
    Molecular Function pyruvate transmembrane transporter activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mpc2-201 (1)    Ensembl 1265
    ncRNA mpc2-002 (1)    Ensembl 826
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mpc2b No data available
    MARKER RELATIONSHIPS
    mpc2b Contained in: [BAC] CH211-119G4 (1), DKEYP-79C5 (1)
    mpc2b Encodes: [EST] fb22b02, fb22g07
    [cDNA] MGC:56391 (1), MGC:86614 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212592 (1) 1117 nt
    Genomic GenBank:BX546477 (1) 58124 nt
    Select Tool
    Polypeptide UniProtKB:Q6IQT9 (1) 127 aa
    Sequence Information (all 17)
    ORTHOLOGY for mpc2b ( Chr: 9 )
    CITATIONS (25)