Gene
cenpt
- ID
- ZDB-GENE-030131-3256
- Name
- centromere protein T
- Symbol
- cenpt Nomenclature History
- Previous Names
-
- fc31h11
- fc75c05
- si:ch211-225g23.1
- wu:fc31h11 (1)
- wu:fc75c05
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity and protein heterodimerization activity. Predicted to be involved in kinetochore assembly. Predicted to localize to kinetochore and nucleus. Used to study Seckel syndrome. Orthologous to human CENPT (centromere protein T).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Babu et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Hung et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Short stature and microcephaly with genital anomalies | 618702 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| Seckel syndrome | WT + MO3-cenpt | standard conditions | Hung et al., 2017 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | CENP-T/Histone H4, histone fold | Centromere protein T | Histone-fold |
|---|---|---|---|---|
|
UniProtKB:A0A8M6Z3Y5
|
901 | |||
|
UniProtKB:E9QIT3
|
914 | |||
|
UniProtKB:A0A8M6YX66
|
919 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
si:ch211-225g23.1-201
(1)
|
Havana | 3125 nt | |
| mRNA |
si:ch211-225g23.1-202
(1)
|
Havana | 543 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance