Gene
hdac6
- ID
- ZDB-GENE-030131-3232
- Name
- histone deacetylase 6
- Symbol
- hdac6 Nomenclature History
- Previous Names
-
- wu:fc31d02
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Exhibits potassium ion binding activity; tubulin deacetylase activity; and zinc ion binding activity. Involved in angiogenesis; hemopoiesis; and protein deacetylation. Orthologous to human HDAC6 (histone deacetylase 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia | Alliance | ?Chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia | 300863 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001607 | Zinc finger, UBP-type |
| Domain | IPR023801 | Histone deacetylase domain |
| Family | IPR000286 | Histone deacetylase family |
| Family | IPR050284 | Histone deacetylase and polyamine deacetylase |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR023696 | Ureohydrolase domain superfamily |
| Homologous_superfamily | IPR037138 | Histone deacetylase domain superfamily |
Domain Details Per Protein
| Protein | Length | Histone deacetylase and polyamine deacetylase | Histone deacetylase domain | Histone deacetylase domain superfamily | Histone deacetylase family | Ureohydrolase domain superfamily | Zinc finger, RING/FYVE/PHD-type | Zinc finger, UBP-type |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F8W4B7
|
1081 | |||||||
|
UniProtKB:A7YT55
|
929 |
Interactions and Pathways
No data available
Plasmids