ZFIN ID: ZDB-GENE-030131-3232
Gene Name: histone deacetylase 6
Gene Symbol: hdac6
Previous Name: wu:fc31d02
Location: Chr: 8 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  anatomical structure, whole organism
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026686Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18529 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34294 Point Mutation Unknown Unknown ENU
    Targeting reagents: CRISPR1-hdac6 (1), CRISPR2-hdac6 (1), CRISPR3-hdac6 (1), CRISPR4-hdac6 (1), MO1-hdac6 (1) (all 8) expand
    PHENOTYPE
    Data: Fig. 2 from Kaluza et al., 2011
    Observed in: dorsal longitudinal anastomotic vessel, intersegmental vessel
    DISEASE ASSOCIATED WITH hdac6 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    ?Chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia 300863
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000286 (1)
  • InterPro:IPR001607 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR023801 (1)
  • PROSITE:PS50271 (1)
  • Pfam:PF00850 (1)
  • Pfam:PF02148 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hdac6-001 (1) 3951
    hdac6-002 (1) 418
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM hdac6 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    hdac6Contained in: [BAC] CH211-150E8 (1) (order this)
    hdac6Contains: [SNP] rs3728138 (1), rs3728139 (1), rs3728140 (1)
    hdac6Encodes: [EST] fc31d02
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009303751 (1) 4268bp
    Genomic GenBank:BX469901 (1) 180553bp
    Select Tool
    Polypeptide UniProtKB:F8W4B7 (1) 1081aa
    Sequence Clusters UniGene:78784 (1)
    Sequence Information (all 15)
    OTHER hdac6 GENE PAGES
  • Gene:565482 (1)
  • VEGA:OTTDARG00000034603 (1)
  • Ensembl(GRCz10):ENSDARG00000008384 (1)
  • ORTHOLOGY for hdac6 (Chr: 8)
    Species Symbol Chromosome Accession # Evidence
    Human HDAC6 X
  • Gene:10013
  • OMIM:300272
  • HGNC:14064
  • Amino acid sequence comparison (2)
    Download Curated Orthology
    CITATIONS (21)