ZFIN ID: ZDB-GENE-030131-3230
Gene Name: striated muscle enriched protein kinase a
Gene Symbol: spega    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: apeg1 (1), speg, SPEG (1), fc31c10, im:6912258, wu:fc31c10 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have protein kinase activity. Predicted to be involved in cardiovascular system development and muscle organ development. Predicted to localize to nucleus. Is expressed in brain. Human ortholog(s) of this gene implicated in centronuclear myopathy 5. Orthologous to human SPEG (striated muscle enriched protein kinase).
Genome Resources: Alliance (1),  Gene:570504 (1),  Ensembl(GRCz11):ENSDARG00000039256 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 4 figures (6 images) from Thisse et al., 2004 [IMAGE:6912258]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa7040 Point Mutation Unknown Splice Site ENU
sa7581 Point Mutation Unknown Missense ENU
sa9635 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12597 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13872 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14081 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14625 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25334 Point Mutation Unknown Premature Stop ENU
    sa26736 Point Mutation Unknown Premature Stop ENU
    sa40677 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40678 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40679 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40680 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40681 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40682 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45251 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-spega N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH spega HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    centronuclear myopathy 5 Alliance Centronuclear myopathy 5 615959
    DISEASE ASSOCIATED WITH spega VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process muscle organ development (more)
    Cellular Component Z disc (more)
    Molecular Function protein kinase activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA spega-202 (1)    Ensembl 9431
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM spega No data available
    MARKER RELATIONSHIPS
    spega Contained in: [BAC] DKEY-91F15 (1) (order this)
    spega Encodes: [EST] fc31c10, IMAGE:6912258 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001007109 (1) 9530 nt
    Genomic GenBank:BX005391 (1) 162632 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IS57 (1) 2995 aa
    Sequence Information (all 15)
    ORTHOLOGY for spega ( Chr: 6 )
    CITATIONS (23)