Gene

spega

ID
ZDB-GENE-030131-3230
Name
striated muscle enriched protein kinase a
Symbol
spega Nomenclature History
Previous Names
  • apeg1 (1)
  • speg
  • SPEG (1)
  • fc31c10
  • im:6912258
  • wu:fc31c10 (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have protein kinase activity. Predicted to be involved in muscle organ development. Predicted to localize to nucleus. Is expressed in brain. Human ortholog(s) of this gene implicated in centronuclear myopathy 5. Orthologous to human SPEG (striated muscle enriched protein kinase).
Genome Resources
Note
None
Expression
All Expression Data
4 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With spega Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
centronuclear myopathy 5 Alliance Centronuclear myopathy 5 615959
Associated With spega Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin subtype
Domain IPR003961 Fibronectin type III
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Family IPR015726 Serine/threonine protein kinase, striated muscle-specific
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length Fibronectin type III Fibronectin type III superfamily Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Immunoglobulin subtype 2 Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Serine/threonine protein kinase, striated muscle-specific
UniProtKB:Q696W0 2995
UniProtKB:Q1LYE8 2995
UniProtKB:A0A0R4IS57 2995
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations