Gene
taf2
- ID
- ZDB-GENE-030131-3207
- Name
- TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor
- Symbol
- taf2 Nomenclature History
- Previous Names
-
- fc30f02
- fc56a05
- wu:fc30f02
- wu:fc56a05
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable chromatin binding activity and transcription cis-regulatory region binding activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 40. Orthologous to human TAF2 (TATA-box binding protein associated factor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
No data available
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 40 | Alliance | Intellectual developmental disorder, autosomal recessive 40 | 615599 |
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Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR037813 | Transcription initiation factor TFIID subunit 2 |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Homologous_superfamily | IPR027268 | Peptidase M4/M1, CTD superfamily |
| Homologous_superfamily | IPR042097 | Aminopeptidase N-like , N-terminal domain superfamliy |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Aminopeptidase N-like , N-terminal domain superfamliy | Armadillo-type fold | Peptidase M4/M1, CTD superfamily | Transcription initiation factor TFIID subunit 2 |
|---|---|---|---|---|---|---|
| UniProtKB:Q32PW3 | InterPro | 1191 | ||||
| UniProtKB:A0A8M9NZ39 | InterPro | 1195 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-93I7 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-59G8 | ZFIN Curated Data | |
| Contains | SNP | rs3728264 | ZFIN Curated Data | |
| Contains | SNP | rs3728265 | ZFIN Curated Data | |
| Contains | SNP | rs3728266 | ZFIN Curated Data | |
| Contains | SNP | rs3728267 | ZFIN Curated Data | |
| Contains | SNP | rs3728268 | ZFIN Curated Data | |
| Contains | SNP | rs3728269 | ZFIN Curated Data | |
| Contains | SNP | rs3728270 | ZFIN Curated Data | |
| Contains | SNP | rs3728271 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001003835 (1) | 4411 nt | ||
| Genomic | GenBank:CU104700 (1) | 155195 nt | ||
| Polypeptide | UniProtKB:A0A8M9NZ39 (1) | 1195 aa |
- Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
- Amsterdam, A., Nissen, R.M., Sun, Z., Swindell, E., Farrington, S., and Hopkins, N. (2004) Identification of 315 genes essential for early zebrafish development. Proceedings of the National Academy of Sciences of the United States of America. 101(35):12792-12797
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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