Gene

plod1a

ID
ZDB-GENE-030131-3165
Name
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a
Symbol
plod1a Nomenclature History
Previous Names
  • lh1 (1)
  • plod1
  • plod (1)
  • fc95g08
  • fi18a05
  • ik:tdsubs_rzpd609-29b19
  • wu:fc29c10
  • wu:fc95g08 (1)
  • wu:fi18a05
  • zgc:152876
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have procollagen-lysine 5-dioxygenase activity. Involved in fin morphogenesis. Predicted to localize to endoplasmic reticulum. Is expressed in several structures, including cranium; notochord; otic vesicle; pectoral fin; and shield. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome. Orthologous to human PLOD1 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 1).
Genome Resources
Note
None
Expression
All Expression Data
6 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. 8 from DurĂ¡n et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With plod1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Ehlers-Danlos syndrome kyphoscoliotic type 1 Alliance Ehlers-Danlos syndrome, kyphoscoliotic type, 1 225400
Associated With plod1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR001006 Procollagen-lysine 5-dioxygenase, conserved site
Domain IPR005123 Oxoglutarate/iron-dependent dioxygenase
Domain IPR006620 Prolyl 4-hydroxylase, alpha subunit
Homologous_superfamily IPR029044 Nucleotide-diphospho-sugar transferases
Domain Details Per Protein
Protein Length Nucleotide-diphospho-sugar transferases Oxoglutarate/iron-dependent dioxygenase Procollagen-lysine 5-dioxygenase, conserved site Prolyl 4-hydroxylase, alpha subunit
UniProtKB:A0JMD1 730
UniProtKB:E9QCW2 50
UniProtKB:A8WIN7 730
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations