Gene

bhlhe40

ID
ZDB-GENE-030131-3133
Name
basic helix-loop-helix family, member e40
Symbol
bhlhe40 Nomenclature History
Previous Names
  • bhlhb2
  • DEC1 (1)
  • Dec1 (1)
  • wu:fc28a06
  • wu:fm54h07
  • zgc:76913
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within circadian regulation of gene expression; locomotor rhythm; and negative regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in several structures, including cardiovascular system; digestive system; immature eye; nervous system; and pleuroperitoneal region. Orthologous to human BHLHE40 (basic helix-loop-helix family member e40).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
25 figures from 12 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Ben-Moshe et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bhlhe40 Human Ortholog
No data available
Associated With bhlhe40 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003650 Orange domain
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Orange domain
UniProtKB:Q6NY50 403
UniProtKB:Q0D311 403
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations