Gene

rgs6

ID
ZDB-GENE-030131-31
Name
regulator of G protein signaling 6
Symbol
rgs6 Nomenclature History
Previous Names
  • hm:zeh0300
  • si:ch211-268e23.2
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have GTPase activator activity. Predicted to be involved in G protein-coupled receptor signaling pathway; intracellular signal transduction; and negative regulation of signal transduction. Is expressed in nervous system and trigeminal placode. Orthologous to human RGS6 (regulator of G protein signaling 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2005
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Thyme et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rgs6 Human Ortholog
No data available
Associated With rgs6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000591 DEP domain
Domain IPR015898 G-protein gamma-like domain
Domain IPR016137 RGS domain
Domain IPR037956 RGS6, RGS domain
Domain IPR040759 Regulator of G-protein signalling, DHEX domain
Family IPR047016 Regulator of G protein signaling 6/7/9/11
Homologous_superfamily IPR036284 G-protein gamma-like domain superfamily
Homologous_superfamily IPR036305 RGS domain superfamily
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Homologous_superfamily IPR044926 RGS, subdomain 2
Homologous_superfamily IPR047017 Regulator of G-protein signalling 6/7/9/11, DHEX domain superfamily
Domain Details Per Protein
Protein Length DEP domain G-protein gamma-like domain G-protein gamma-like domain superfamily Regulator of G protein signaling 6/7/9/11 Regulator of G-protein signalling 6/7/9/11, DHEX domain superfamily Regulator of G-protein signalling, DHEX domain RGS6, RGS domain RGS domain RGS domain superfamily RGS, subdomain 2 Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:Q38JL1 489
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA rgs6-201 (1) Havana 5341 nt
mRNA rgs6-202 (1) Ensembl 1497 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations