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ZIRC
ZFIN ID: ZDB-GENE-030131-3063
Gene Name: complement component c3b, tandem duplicate 2
Gene Symbol: c3b.2
Sequence Ontology ID : SO:0001217

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Previous Names: c3.8 (1), si:ch211-140f21.1, wu:fc26b08

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(Including Attributions)
Location: Chr: 22 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have endopeptidase inhibitor activity. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in several diseases, including complement deficiency  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa30731 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32403 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43859 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH c3b.2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    age related macular degeneration 9 {Macular degeneration, age-related, 9} 611378
    complement component 3 deficiency C3 deficiency 613779
    {Hemolytic uremic syndrome, atypical, susceptibility to, 5} 612925
    DISEASE ASSOCIATED WITH c3b.2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component extracellular region (more)
    Molecular Function endopeptidase inhibitor activity (more)
    GO Terms (all 3)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA c3b.2-201 (1) 5732
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM c3b.2 No data available
    MARKER RELATIONSHIPS
    c3b.2 Contained in: [BAC] CH211-140F21 (1) (order this)
    c3b.2 Encodes: [EST] fc26b08
    [cDNA] MGC:171869 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001100020 (1) 5737 bp
    Genomic GenBank:BX649330 (1) 163964 bp
    Select Tool
    Polypeptide UniProtKB:A5PMP8 (1) 1690 aa
    Sequence Clusters UniGene:78847 (1)
    Sequence Information (all 21)
    ORTHOLOGY for c3b.2 ( Chr: 22 )
    CITATIONS (15)