ZFIN ID: ZDB-GENE-030131-3060
Gene Name: cytochrome P450, family 3, subfamily c, polypeptide 1
Gene Symbol: cyp3c1    Nomenclature History

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Previous Names: CYP3A (1), wu:fa96d12, wu:fc26b04, zgc:56626

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Exhibits heme binding activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to the integral component of membrane. Is expressed in several structures, including digestive system; heart; integument; nervous system; and pleuroperitoneal region. Orthologous to several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4).
Genome Resources: Alliance (1),  Gene:324340 (1),  Ensembl(GRCz11):ENSDARG00000015575 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2102 Point Mutation Unknown Splice Site ENU
sa33276 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cyp3c1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cyp3c1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function heme binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR001128 Cytochrome P450
    Family IPR002401 Cytochrome P450, E-class, group I
    Family IPR008072 Cytochrome P450, E-class, CYP3A
    Conserved_site IPR017972 Cytochrome P450, conserved site
    Homologous_superfamily IPR036396 Cytochrome P450 superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cyp3c1-201 (1)    Ensembl 1931
    cyp3c1-202 (1)    Ensembl 617
    cyp3c1-203 (1)    Ensembl 530
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cyp3c1 No data available
    MARKER RELATIONSHIPS
    cyp3c1 Contained in: [BAC] DKEY-21N8 (1) (order this)
    cyp3c1 Encodes: [EST] fa96d12 (1), fc26b04
    [cDNA] MGC:56626 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212673 (1) 1899 bp
    Genomic GenBank:BX649536 (1) 203180 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1QPC1 (1) 505 aa
    Sequence Information (all 17)
    ORTHOLOGY for cyp3c1 ( Chr: 3 )
    CITATIONS (37)